Exon 2 of Foxp3 controls Treg seeding of peripheral tissue, and maybe their stability

A publication in Science Immunology, titled ‘FOXP3 exon 2 controls Treg stability and autoimmunity’, explores how Foxp3 gene might function. The paper can be accessed here. Background The regulatory T cells (Tregs) are an important immune cell that suppresses other immune cells. They are important for suppressing activation of immune cells against our own body. A gene called Foxp3 is critical for the function and … Continue reading Exon 2 of Foxp3 controls Treg seeding of peripheral tissue, and maybe their stability

Immune cells and stem cells

In this post, we discuss a publication in Nature Immunology, titled ‘Glucocorticoid signaling and regulatory T cells cooperate to maintain the hair-follicle stem-cell niche’. The paper can be accessed here. This paper examines the role of regulatory T cells (Tregs). Tregs are a subset of immune cells that are known for its ability to control and suppress other immune cells. Their function is extremely important … Continue reading Immune cells and stem cells